Hepatocellular carcinoma in a free-living marmoset (Callithrix sp.) with concomitant biliary trematodiasis

J Med Primatol. 2018 Apr;47(2):128-131. doi: 10.1111/jmp.12329. Epub 2017 Dec 28.

Abstract

Hepatocellular carcinoma (HCC) is rare in New World primates. We report the gross, microscopical, and immunocytochemical features of a spontaneous HCC in a free-living marmoset (Callithrix sp.). Hepatitis B and C virus and aflatoxin immunohistochemistry were negative; however, concomitant intra- and extrahepatic biliary trematodiasis could have played a role.

Keywords: New World primate; cancer; hepatopathy; neoplasia; non-human primate; yellow fever.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Bile Duct Diseases / complications
  • Bile Duct Diseases / parasitology*
  • Callithrix*
  • Carcinoma, Hepatocellular / etiology
  • Carcinoma, Hepatocellular / pathology
  • Carcinoma, Hepatocellular / veterinary*
  • Immunohistochemistry / veterinary
  • Liver Neoplasms / etiology
  • Liver Neoplasms / pathology
  • Liver Neoplasms / veterinary*
  • Monkey Diseases / etiology
  • Monkey Diseases / pathology*
  • Trematode Infections / complications
  • Trematode Infections / parasitology
  • Trematode Infections / veterinary*