The new genetics of intelligence

Nat Rev Genet. 2018 Mar;19(3):148-159. doi: 10.1038/nrg.2017.104. Epub 2018 Jan 8.

Abstract

Intelligence - the ability to learn, reason and solve problems - is at the forefront of behavioural genetic research. Intelligence is highly heritable and predicts important educational, occupational and health outcomes better than any other trait. Recent genome-wide association studies have successfully identified inherited genome sequence differences that account for 20% of the 50% heritability of intelligence. These findings open new avenues for research into the causes and consequences of intelligence using genome-wide polygenic scores that aggregate the effects of thousands of genetic variants.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Genome-Wide Association Study
  • Human Genetics / methods
  • Humans
  • Intelligence / genetics*
  • Polymorphism, Single Nucleotide*
  • Quantitative Trait, Heritable*