Loss of Toll-like receptor 2 results in accelerated leukemogenesis in the NUP98-HOXD13 mouse model of MDS

Blood. 2018 Mar 1;131(9):1032-1035. doi: 10.1182/blood-2017-08-801944. Epub 2018 Jan 22.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Transformation, Neoplastic* / genetics
  • Cell Transformation, Neoplastic* / metabolism
  • Cell Transformation, Neoplastic* / pathology
  • Disease Models, Animal
  • Homeodomain Proteins* / genetics
  • Homeodomain Proteins* / metabolism
  • Mice
  • Myelodysplastic Syndromes* / genetics
  • Myelodysplastic Syndromes* / metabolism
  • Myelodysplastic Syndromes* / pathology
  • Nuclear Pore Complex Proteins* / genetics
  • Nuclear Pore Complex Proteins* / metabolism
  • Oncogene Proteins, Fusion* / genetics
  • Oncogene Proteins, Fusion* / metabolism
  • Toll-Like Receptor 2 / deficiency*
  • Transcription Factors* / genetics
  • Transcription Factors* / metabolism

Substances

  • Homeodomain Proteins
  • Hoxd13 protein, mouse
  • Nuclear Pore Complex Proteins
  • Oncogene Proteins, Fusion
  • Tlr2 protein, mouse
  • Toll-Like Receptor 2
  • Transcription Factors
  • nuclear pore complex protein 98