[Pulmonary granuloma in an immunodepressed patient]

Abstract

Introduction: Pulmonary alveolar echinococcosis is a rare but potentially severe condition.

Case report: We report the case of a 50-year-old woman suffering from pulmonary alveolar echinococcosis who had had a renal transplant for polycystic liver and kidney disease. A lung opacity was identified radiologically in May 2013. Both broncho-alveolar lavage and bronchial biopsy were uninformative. In January 2014, a follow up CT-scan showed the opacity to be enlarging. A surgical biopsy revealed a giant cell epithelioid granuloma with caseous necrosis suggesting a diagnosis of pulmonary tuberculosis. Antituberculous treatment was started but cultures remained negative. A histological revue was therefore requested in March 2014. This suggested bronchocentric granulmatosis, possibly associated with echinococcosis. This hypothesis was finally confirmed serologically. Treatment for alveolar echinococcosis was begun in June 2014 after consultation with the national reference centre for parasitology.

Conclusion: Outside endemic areas and in the absence of hepatic involvement pulmonary alveolar echinococcosis can be difficult to diagnose. This case report focuses on the diagnostic criteria and treatment.

Keywords: Alveolar echinococcosis; Bronchocentric granulomatosis; Granulome bronchocentrique; Granulome pulmonaire; Greffe rénale; Immunodeficiency; Immunodéficience; Pulmonary granuloma; Renal transplantation; Échinococcose alvéolaire.