Acute Appendicitis as the Initial Clinical Presentation of Primary HIV-1 Infection

Open Forum Infect Dis. 2018 Jan 9;5(2):ofy006. doi: 10.1093/ofid/ofy006. eCollection 2018 Feb.

Abstract

We report a case of an adolescent who presented at our emergency department with acute abdominal pain. While the initial diagnosis was acute appendicitis, a secondary and coincidental diagnosis of primary HIV-1 infection was made. Concurrent and subsequent clinical and molecular biology findings form the basis of our argument that primary HIV-1 infection was the cause of acute appendicitis in this individual.

Keywords: acute appendicitis; diagnosis; immunohistochemistry; in situ hybridization; primary HIV-1.