Heart Failure with Hyperthyroidism Demonstrating Discrepancy between the Clinical Course and B-type Natriuretic Peptide Levels

Intern Med. 2018 Jun 15;57(12):1747-1749. doi: 10.2169/internalmedicine.0118-17. Epub 2018 Feb 9.

Abstract

A 35-year-old Japanese man was emergently admitted to our hospital with chief complaints of palpitation and dyspnea. He has been treated for Basedow's disease. He was diagnosed with acute decompensated heart failure, atrial fibrillation and thyrotoxicosis. We started anti-thyroid agents and a treatment for heart failure with beta blockers and diuretics under anti-coagulation therapy. His B-type natriuretic peptide levels remained high, although the heart failure had been compensated and the heart rate was well controlled while hyperthyroidism still existed. We should bear in mind that a discrepancy can exist between the clinical course and the B-type natriuretic peptide level in heart failure patients complicated with hyperthyroidism.

Keywords: BNP; heart failure; hyperthyroidism.

Publication types

  • Case Reports

MeSH terms

  • Adrenergic beta-Antagonists / therapeutic use
  • Adult
  • Anticoagulants / therapeutic use
  • Atrial Fibrillation / complications
  • Atrial Fibrillation / drug therapy
  • Diuretics / therapeutic use
  • Heart Failure / complications*
  • Heart Failure / drug therapy
  • Heart Failure / physiopathology*
  • Humans
  • Hyperthyroidism / complications*
  • Hyperthyroidism / physiopathology*
  • Male
  • Natriuretic Peptide, Brain / blood*
  • Thyrotoxicosis / drug therapy

Substances

  • Adrenergic beta-Antagonists
  • Anticoagulants
  • Diuretics
  • Natriuretic Peptide, Brain