Updates of Peripheral T Cell Lymphomas Based on the 2017 WHO Classification

Curr Hematol Malig Rep. 2018 Feb;13(1):25-36. doi: 10.1007/s11899-018-0429-y.

Abstract

Purpose of review: This review will describe and update the readers on the recent changes of the 2017 WHO classification in regard to peripheral T cell lymphomas.

Recent findings: Significant advances in molecular studies have resulted in revisions of the classification as well as introduction of provisional entities (such as breast implant-associated ALCL, nodal PTCL with TFH phenotype). Major advances in molecular and gene expression profiling have expanded our knowledge of T cell lymphomas, including updates in the diagnostic criteria and sub-classification which will facilitate in improving patient care and research.

Keywords: Classification; Molecular; Pathology; Peripheral T cell lymphoma.

Publication types

  • Review

MeSH terms

  • Gene Expression Profiling
  • Gene Expression Regulation, Neoplastic*
  • Humans
  • Lymphoma, T-Cell, Peripheral / classification*
  • Lymphoma, T-Cell, Peripheral / genetics*
  • Lymphoma, T-Cell, Peripheral / metabolism*
  • World Health Organization