A rare case of oral metastasis of colon adenocarcinoma

I Romanet; R Lan; U Ordioni; A F Albertini; F Campana

doi:10.1016/j.jormas.2018.02.003

A rare case of oral metastasis of colon adenocarcinoma

J Stomatol Oral Maxillofac Surg. 2018 Jun;119(3):229-231. doi: 10.1016/j.jormas.2018.02.003. Epub 2018 Feb 21.

Authors

I Romanet¹, R Lan¹, U Ordioni², A F Albertini³, F Campana⁴

Affiliations

¹ Service d'odontologie, Aix Marseille University, AP-HM, La Timone, 264, rue Saint-Pierre, 13385 Marseille cedex 5, France.
² Centre massilien de la face, 13006 Marseille, France.
³ Anatomopathology laboratory, MEDIPATH, 06250 Mougins, France.
⁴ Service d'odontologie, Aix Marseille University, AP-HM, La Timone, 264, rue Saint-Pierre, 13385 Marseille cedex 5, France. Electronic address: fabrice.campana@univ-amu.fr.

PMID: 29475082
DOI: 10.1016/j.jormas.2018.02.003

Abstract

Introduction: Metastatic carcinoma of the colon is frequently encountered. In the literature, metastasis of malignant tumors in the buccal cavity are rare. They represent less than 1% of oral malignant lesions.

Observation: We present a case of oral metastasis of colon adenocarcinoma in the mandible of a 62-year-old patient. The physical examination revealed a swelling in the mandibular symphysis associated with dental displacement. The panoramic X-ray showed significant bone lysis of the symphysis. The neoplastic tissue showed marked positivity for Cytokeratin 20 and CDX2, confirming the diagnosis of metastasis of the oral cavity from colorectal adenocarcinoma.

Discussion: Metastatic adenocarcinoma from the colon to the oral cavity are rare but should be included in the differential diagnosis of tumors in the oral cavity.

Keywords: Colonic neoplasms; Neoplasm metastasis; Oral.

Publication types

Case Reports

MeSH terms

Adenocarcinoma*
Colonic Neoplasms*
Colorectal Neoplasms*
Humans
Keratin-20
Middle Aged

Substances

Keratin-20