Increased lymphocyte cell size with blastoid morphology associated with splenic rupture following cessation of ibrutinib

Br J Haematol. 2018 May;181(4):431. doi: 10.1111/bjh.15134. Epub 2018 Feb 26.

Authors

Edit Porpaczy¹, Cathrin Skrabs¹, Ilse Schwarzinger², Dorothea Augustin², Renate Thalhammer², Ulrich Jaeger¹

Affiliations

¹ Department of Internal Medicine I, Division of Haematology and Haemostaseology, Comprehensive Cancer Centre, Medical University of Vienna, Vienna, Austria.
² Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.

PMID: 29479671
DOI: 10.1111/bjh.15134

No abstract available

Publication types

Case Reports

MeSH terms

Adenine / analogs & derivatives
Aged
Humans
Leukemia, Lymphocytic, Chronic, B-Cell* / drug therapy
Leukemia, Lymphocytic, Chronic, B-Cell* / pathology
Lymphocytes / pathology*
Male
Piperidines
Pyrazoles* / administration & dosage
Pyrazoles* / adverse effects
Pyrimidines* / administration & dosage
Pyrimidines* / adverse effects
Splenic Rupture* / chemically induced
Splenic Rupture* / pathology

Substances

Piperidines
Pyrazoles
Pyrimidines
ibrutinib
Adenine