Prevalence, Causes, and Predictors of 30-Day Readmissions Following Hospitalization With Acute Myocardial Infarction Complicated By Cardiogenic Shock: Findings From the 2013-2014 National Readmissions Database

J Am Heart Assoc. 2018 Mar 23;7(6):e008235. doi: 10.1161/JAHA.117.008235.

Abstract

Background: Prior studies have shown that survivors of acute myocardial infarction (AMI) complicated by cardiogenic shock are likely to have increased risk of readmissions in the early post-discharge period. However, the contemporary prevalence, reasons, and predictors of 30-day readmissions are not well known.

Methods and results: Hospitalizations for a primary diagnosis of AMI complicated by cardiogenic shock, and discharged alive, were identified in the 2013 and 2014 Nationwide Readmissions Databases. Prevalence and reasons for 30-day unplanned readmissions were investigated. A hierarchical logistic regression model was used to identify independent predictors of 30-day readmissions. Among 1 116 933 patient hospitalizations with AMI, 39 807 (3.6%) had cardiogenic shock and were discharged alive. Their 30-day readmission rate was 18.6%, with a median time for readmission 10 days post discharge. Predictors of readmission included: non-ST-segment elevation myocardial infarction, female sex, low-income status, nonprivate insurance, chronic renal failure, long-term ventricular assist device or intra-aortic balloon placement, and tachyarrhythmia. The majority of readmissions were attributable to cardiac-related causes (52%); heart failure being the most frequent cardiac cause (39% of all cardiac causes). Noncardiac-related readmissions included infections (14.9%), bleeding (5.3%), and respiratory causes (4.9%). The median cost per readmission was $9473 US dollars ($5037-20 199).

Conclusions: Among survivors of AMI complicated by cardiogenic shock who were discharged from hospital, almost 1 in 5 are readmitted at 30 days, mainly because of cardiac reasons such as heart failure and new AMI. The risk of readmission was associated with certain baseline patient/hospital characteristics.

Keywords: cardiogenic shock; heart failure; myocardial infarction; readmission.

Publication types

  • Observational Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Databases, Factual
  • Female
  • Health Status
  • Hospital Costs
  • Humans
  • Male
  • Myocardial Infarction / diagnosis
  • Myocardial Infarction / economics
  • Myocardial Infarction / epidemiology
  • Myocardial Infarction / therapy*
  • Patient Discharge
  • Patient Readmission* / economics
  • Prevalence
  • Recurrence
  • Risk Assessment
  • Risk Factors
  • Shock, Cardiogenic / diagnosis
  • Shock, Cardiogenic / economics
  • Shock, Cardiogenic / epidemiology
  • Shock, Cardiogenic / therapy*
  • Time Factors
  • United States / epidemiology