Neuroblastic tumors in young adults as a sequela of malignant neuroblastoma: report of two cases

Abdom Radiol (NY). 2018 Jul;43(7):1531-1534. doi: 10.1007/s00261-018-1586-0.

Abstract

Neuroblastoma, ganglioneuroblastoma, and ganglioneuroma share the same histological spectrum which originates from neural crest cells. We present herein two young adult patients with neuroblastic tumors with lymph node metastases. Both the patients were diagnosed incidentally as having retroperitoneal masses, which showed little or no immature cells despite coexistence of lymph node involvement. The tumors were considered to represent spontaneous regression of malignant neuroblastoma. Radiologists should consider the possibility of spontaneous regression of neuroblastic tumors, when poorly enhanced multi-component masses at the retroperitoneum with lymph node involvement are visualized.

Keywords: Ganglioneuroblastoma; Ganglioneuroma; Neuroblastic tumors; Neuroblastoma; Spontaneous regression.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Disease Progression
  • Female
  • Humans
  • Incidental Findings
  • Lymph Nodes / diagnostic imaging
  • Lymphatic Metastasis / diagnostic imaging*
  • Male
  • Neuroblastoma / diagnostic imaging*
  • Retroperitoneal Neoplasms / diagnostic imaging*
  • Retroperitoneal Space / diagnostic imaging
  • Tomography, X-Ray Computed / methods*
  • Young Adult