The Potential Mechanisms of Exercise-induced Cognitive Protection: A Literature Review

Jennifer E Norman; Jennifer Rutkowsky; Sue Bodine; John C Rutledge

doi:10.2174/1381612824666180406105149

The Potential Mechanisms of Exercise-induced Cognitive Protection: A Literature Review

Curr Pharm Des. 2018;24(17):1827-1831. doi: 10.2174/1381612824666180406105149.

Authors

Jennifer E Norman¹, Jennifer Rutkowsky², Sue Bodine³, John C Rutledge¹

Affiliations

¹ Department of Internal Medicine, Division of Cardiovascular Medicine, University of California, Davis, CA, United States.
² Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, CA, United States.
³ Department of Internal Medicine, Division of Endocrinology and Metabolism, University of Iowa, Iowa City, IA, United States.

Abstract

Dementia has become a major health concern for the aging population of the United States. Studies indicate that participation in moderate exercise, with training, has been shown to have a beneficial impact on cognition. Thus, exercise and its effects on cognitive function has become an important area of research. This review summarizes the current literature on the potential mechanisms of the benefits of exercise for cognitive function.

Keywords: BDNF; Cognitive function; IL-6; PGC-1α; dementia; exercise..

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review

MeSH terms

Cognition*
Dementia / prevention & control*
Exercise*
Humans

Abstract

Publication types

MeSH terms

Grants and funding