Imaging Macrophage-associated Inflammation

Catherine A Foss; Julian Sanchez-Bautista; Sanjay K Jain

doi:10.1053/j.semnuclmed.2017.12.002

Imaging Macrophage-associated Inflammation

Semin Nucl Med. 2018 May;48(3):242-245. doi: 10.1053/j.semnuclmed.2017.12.002. Epub 2018 Feb 13.

Authors

Catherine A Foss¹, Julian Sanchez-Bautista², Sanjay K Jain³

Affiliations

¹ Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, MD; Center for Infection and Inflammation Imaging Research, Johns Hopkins University School of Medicine, Baltimore, MD.
² Center for Infection and Inflammation Imaging Research, Johns Hopkins University School of Medicine, Baltimore, MD; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD.
³ Center for Infection and Inflammation Imaging Research, Johns Hopkins University School of Medicine, Baltimore, MD; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD. Electronic address: sjain5@jhmi.edu.

Abstract

Macrophages belong to the mononuclear phagocyte system comprising closely related cells of bone marrow origin. Activated macrophages are critical in several diseases such as tuberculosis, sarcoidosis, Crohn's disease, and atherosclerosis. Noninvasive imaging techniques that can specifically image activated macrophages could therefore help in differentiating various forms of inflammatory diseases and to monitor therapeutic responses.

Publication types

Research Support, N.I.H., Extramural
Review

MeSH terms

Animals
Humans
Inflammation / diagnostic imaging*
Inflammation / immunology*
Macrophages / metabolism*
Molecular Imaging / methods*

Abstract

Publication types

MeSH terms

Grants and funding