Objective: To report a rare successful pregnancy after fertility treatment in a patient with Swyer syndrome.
Design: Case report.
Setting: Herts & Essex Fertility Centre, Cheshunt, UK.
Patients: A 36-year-old patient with 46, XY gonadal dysgenesis. 31 year old husband with normal sperm analysis.
Interventions: Chromosomal analysis, Saline infusion sonography, Pipelle endometrial scratch, ICSI using donor eggs, Embryo Transfer, and Caesarean delivery.
Main outcome measures: Successful pregnancy and live birth.
Results: Successful treatment with donor eggs, pregnancy, and delivery.
Conclusions: A patient with 46, XY gonadal dysgenesis in a specially tailored fertility program, can maintain a normal pregnancy and delivery.
Keywords: Gonadal dysgenesis; Pregnancy in Swyer syndrome; Primary amenorrhoea and HRT; Swyer syndrome; XY female.