Usefulness of Kaposi's Sarcoma-Associated Herpesvirus (KSHV) DNA Viral Load in Whole Blood for Diagnosis and Monitoring of KSHV-Associated Diseases

Aude Jary; Valentin Leducq; Romain Palich; Adélie Gothland; Diane Descamps; Véronique Joly; Sidonie Lambert-Niclot; Corinne Amiel; Ana Canestri; Audrey Mirand; Elyanne Gault; Astrid Vabret; Marc-Antoine Valantin; Christine Katlama; Vincent Calvez; Nicolas Dupin; Jean-Philippe Spano; Anne-Geneviève Marcelin

doi:10.1128/JCM.00569-18

Usefulness of Kaposi's Sarcoma-Associated Herpesvirus (KSHV) DNA Viral Load in Whole Blood for Diagnosis and Monitoring of KSHV-Associated Diseases

J Clin Microbiol. 2018 May 25;56(6):e00569-18. doi: 10.1128/JCM.00569-18. Print 2018 Jun.

Authors

Aude Jary¹, Valentin Leducq², Romain Palich³, Adélie Gothland², Diane Descamps⁴, Véronique Joly⁵, Sidonie Lambert-Niclot⁶, Corinne Amiel⁷, Ana Canestri⁸, Audrey Mirand⁹, Elyanne Gault¹⁰, Astrid Vabret¹¹, Marc-Antoine Valantin³, Christine Katlama³, Vincent Calvez², Nicolas Dupin¹², Jean-Philippe Spano¹³, Anne-Geneviève Marcelin¹

Affiliations

¹ Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), AP-HP, Hôpital Pitié Salpêtrière, Laboratoire de virologie, Paris, France aude.jary@aphp.fr anne-genevieve.marcelin@aphp.fr.
² Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), AP-HP, Hôpital Pitié Salpêtrière, Laboratoire de virologie, Paris, France.
³ Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), AP-HP, Hôpital Pitié Salpêtrière, Service de Maladies Infectieuses et Tropicale, Paris, France.
⁴ IAME, UMR 1137, INSERM, Université Paris Diderot, Sorbonne Paris Cité, AP-HP, Service de Virologie, Hôpital Bichat, AP-HP, Paris, France.
⁵ IAME, UMR 1137, INSERM, Université Paris Diderot, Sorbonne Paris Cité, AP-HP, Service de Maladies Infectieuses et Tropicales, Hôpital Bichat, AP-HP, Paris, France.
⁶ Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), AP-HP, Hôpital Saint Antoine, Service de Virologie, Paris, France.
⁷ Service de Virologie, AP-HP Hôpital Tenon, Paris, France.
⁸ Service de Maladies Infectieuses et Tropicale, AP-HP Hôpital Tenon, Paris, France.
⁹ Service de Virologie, CHU Clermont-Ferrand, Clermont-Ferrand, France.
¹⁰ Service de Microbiologie-Hygiène, AP-HP Hôpital Ambroise Paré, Boulogne-Billancourt, France.
¹¹ Service de Virologie, CHU Caen, Caen, France.
¹² Service de Dermatologie, Hôpital Tarnier, GH Cochin-Port Royal, Paris, France.
¹³ Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), AP-HP, Hôpital Pitié Salpêtrière, Service d'Oncologie Médicale, Paris, France.

No abstract available

Keywords: DNA; Kaposi's sarcoma-associated diseases; Kaposi's sarcoma-associated herpesvirus; biomarker; whole blood.

Publication types

Letter

MeSH terms

Adult
Aged
Aged, 80 and over
Castleman Disease / blood
Castleman Disease / diagnosis
Castleman Disease / virology
DNA, Viral / blood*
Female
HIV Infections / complications
HIV Infections / virology
Herpesviridae Infections / blood*
Herpesviridae Infections / complications
Herpesviridae Infections / diagnosis*
Herpesvirus 8, Human / genetics*
Humans
Lymphoma, Primary Effusion / blood
Lymphoma, Primary Effusion / diagnosis
Lymphoma, Primary Effusion / virology
Male
Middle Aged
Real-Time Polymerase Chain Reaction
Retrospective Studies
Sarcoma, Kaposi / blood*
Sarcoma, Kaposi / diagnosis
Viral Load*
Young Adult

Substances

DNA, Viral