Heartland Virus and Hemophagocytic Lymphohistiocytosis in Immunocompromised Patient, Missouri, USA

Emerg Infect Dis. 2018 May;24(5):893-897. doi: 10.3201/eid2405.171802.

Abstract

Heartland virus is a suspected tickborne pathogen in the United States. We describe a case of hemophagocytic lymphohistiocytosis, then death, in an immunosuppressed elderly man in Missouri, USA, who was infected with Heartland virus.

Keywords: Bunyaviridae; Hantaviridae Missouri; Phenuiviridae; Phlebovirus; United States; arbovirus; heartland virus; hemophagocytic lymphohistiocytosis; immunocompromised; viruses.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antibodies, Viral / blood
  • Bunyaviridae Infections / blood
  • Bunyaviridae Infections / complications*
  • Bunyaviridae Infections / epidemiology
  • Bunyaviridae Infections / virology*
  • Fatal Outcome
  • Humans
  • Immunocompromised Host
  • Lymphohistiocytosis, Hemophagocytic / complications*
  • Lymphohistiocytosis, Hemophagocytic / epidemiology*
  • Male
  • Missouri / epidemiology
  • Phlebovirus / genetics
  • Phlebovirus / isolation & purification*

Substances

  • Antibodies, Viral