Transfusion policy in allogeneic hematopoietic stem cell transplantation

Transfus Apher Sci. 2018 Apr;57(2):174-177. doi: 10.1016/j.transci.2018.04.017. Epub 2018 Apr 18.

Abstract

The incompatibility of ABO blood group between the recipient and the donor is not a barrier to perform allogeneic hematopoietic stem cell transplantation (Allo-HSCT). However, ABO incompatibility may lead to many complications during and after stem cell transplantation at the early or late period. Therefore, the typing of the blood group of the recipient and the donor should be done prior to the transplantation. In addition, the ABO/Rh group of blood products for transfusion should be determined according to the type of ABO-incompatibility. In this review, the subtypes of ABO blood group-incompatibility and transfusion policies will be discussed in detail.

Keywords: ABO incompatibility; Allogeneic hematopoetic stem cell transplantation; Blood group; Transfusion.

Publication types

  • Review

MeSH terms

  • ABO Blood-Group System / metabolism*
  • Adult
  • Blood Transfusion / methods*
  • Female
  • Hematopoietic Stem Cell Transplantation / methods*
  • Humans
  • Male
  • Transplantation Conditioning / methods*
  • Transplantation, Homologous / methods*

Substances

  • ABO Blood-Group System