Overweight/obesity enhances associations between secondhand smoke exposure and asthma morbidity in children

Tianshi David Wu; Emily P Brigham; Roger Peng; Kirsten Koehler; Cynthia Rand; Elizabeth C Matsui; Gregory B Diette; Nadia N Hansel; Meredith C McCormack

doi:10.1016/j.jaip.2018.04.020

Overweight/obesity enhances associations between secondhand smoke exposure and asthma morbidity in children

J Allergy Clin Immunol Pract. 2018 Nov-Dec;6(6):2157-2159.e5. doi: 10.1016/j.jaip.2018.04.020. Epub 2018 May 3.

Authors

Tianshi David Wu¹, Emily P Brigham¹, Roger Peng², Kirsten Koehler³, Cynthia Rand¹, Elizabeth C Matsui⁴, Gregory B Diette⁵, Nadia N Hansel⁵, Meredith C McCormack⁶

Affiliations

¹ Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Md.
² Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Md.
³ Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Md.
⁴ Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Md; Division of Pediatric Allergy and Immunology, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, Md.
⁵ Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Md; Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Md.
⁶ Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Md; Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Md. Electronic address: mmccor16@jhmi.edu.

Abstract

In two observational cohorts of inner-city children with asthma, secondhand smoke exposure was associated with worsened symptoms in overweight/obese compared to normal weight children, suggesting that elevated BMI may increase susceptibility to secondhand smoke, a common indoor pollutant.

Publication types

Letter
Observational Study
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Air Pollution, Indoor / adverse effects
Asthma / epidemiology*
Body Mass Index
Child
Cohort Studies
Comorbidity
Environmental Exposure / adverse effects
Environmental Exposure / statistics & numerical data*
Female
Humans
Male
Obesity / epidemiology*
Overweight
Tobacco Smoke Pollution / adverse effects
Tobacco Smoke Pollution / statistics & numerical data*
United States / epidemiology
Urban Population*

Substances

Tobacco Smoke Pollution

Abstract

Publication types

MeSH terms

Substances

Grants and funding