A technology developed from concept of acupuncture and meridian system, the clinical effect of BIOCERAMIC resonance on psychological related sleep disturbance with findings on questionnaire, EEG and fMRI

Lei Zhang; Paul Chan; Zhong Min Liu; Yi Li Tseng; C Will Chen; Ming Tse Lin; Wing P Chan; Ting-Kai Leung

doi:10.1016/j.jtcme.2017.04.004

A technology developed from concept of acupuncture and meridian system, the clinical effect of BIOCERAMIC resonance on psychological related sleep disturbance with findings on questionnaire, EEG and fMRI

J Tradit Complement Med. 2017 May 8;8(2):289-295. doi: 10.1016/j.jtcme.2017.04.004. eCollection 2018 Apr.

Authors

Lei Zhang¹, Paul Chan², Zhong Min Liu³, Yi Li Tseng⁴, C Will Chen⁵, Ming Tse Lin⁵, Wing P Chan⁶, Ting-Kai Leung^{7

8}

Affiliations

¹ Department of Radiology, Shanghai East Hospital, Tongji University, Shanghai, China.
² Division of Cardiology, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
³ Department of Cardiac Surgery, Shanghai East Hospital, Tongji University, Shanghai, China.
⁴ Department of Electrical Engineering, Fu Jen Catholic University, Taiwan.
⁵ Department of Bioengineering, Tatung University, No. 40, Sec. 3, Zhongshan N. Road, Taipei, 104, Taiwan.
⁶ Department of Radiology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
⁷ Department of Radiology, Taoyuan General Hospital, Ministry of Health and Welfare, No. 1492, Zhongshan Rd., Taoyuan Dist., Taoyuan, 330, Taiwan.
⁸ Graduate Institute of Biomedical Materials and Tissue Engineering, College of Medical Engineering, Taipei Medical University, Taipei, Taiwan.

Abstract

Under the concept of meridian channels that belongs to traditional Chinese medicine, BIOCERAMIC Resonance (BR) has already been applied to many clinical medical research projects with functions mimicking of traditional acupuncture. Forty-five patients were recruited with chronic sleep disorders; 36 patients were given, applied to the device with BIOCERAMIC material and sound rhythm on chest skin surface; 9 patients were included as controls. All study participants completed a sleep pattern and quality of life questionnaire (assessment on psychological and physical causes of sleep disturbances), which was repeated before, during and after treatment. Electroencephalograph (EEG) recordings were analyzed before, during and after treatment. Functional MRI (fMRI) was also used for demonstration of BR effect for another 8 candidates. During the first 3 days of treatment, sleep quality improved in all 36 patients especially to psychological reasons; in 91.7% (33/36) treatment was associated with an elevation in the beta spectrum of the EEG (at 15-27 Hz). The result of fMRI found corresponding cerebral and cerebellar areas of activation and deactivation. BIOCERAMIC Resonance can improve sleep disorder due to psychological causes, with transient alter brain wave activity and functional activation on specific locations of brain.

Keywords: BIOCERAMIC; EEG; Sleep disturbance; Sound rhythm; fMRI.