Similar effect of quercetin on CYP2E1 and CYP2C9 activities in humans?

Eur J Clin Pharmacol. 2018 Sep;74(9):1187-1188. doi: 10.1007/s00228-018-2479-4. Epub 2018 May 17.

Authors

Shingen Misaka¹, Kenju Shimomura²

Affiliations

¹ Department of Pharmacology, School of Medicine, Fukushima Medical University, 1 Hikarigaoka, Fukushima, 960-1295, Japan. misaka@fmu.ac.jp.
² Department of Pharmacology, School of Medicine, Fukushima Medical University, 1 Hikarigaoka, Fukushima, 960-1295, Japan.

PMID: 29770840
DOI: 10.1007/s00228-018-2479-4

No abstract available

Publication types

Letter

MeSH terms

Chlorzoxazone / pharmacokinetics
Chlorzoxazone / pharmacology
Cytochrome P-450 CYP2C9 / metabolism*
Cytochrome P-450 CYP2E1 / drug effects*
Cytochrome P-450 CYP2E1 / metabolism*
Diclofenac / pharmacokinetics
Drug Interactions
Humans
Quercetin / pharmacology*

Substances

Diclofenac
Quercetin
Cytochrome P-450 CYP2C9
Cytochrome P-450 CYP2E1
Chlorzoxazone