Bilateral Conjunctival Granulomas in a Young Lady with Hypereosinophilic Syndrome - A Case Report

Ocul Immunol Inflamm. 2019;27(5):805-807. doi: 10.1080/09273948.2018.1468472. Epub 2018 May 17.

Abstract

Purpose: To report an interesting case of bilateral conjunctival granulomas in a young lady with hypereosiniophilic syndrome. Materials & Methods: Retrospective interventional case report Results: A 37-year-old lady presented with irritation and redness in both eyes of 15-day duration. She had a history of abdominal pain and diarrhea since 8 months for which she has been extensively investigated including a positron emission tomography (PET) scan and an ileal biopsy which showed chronic granulomatous inflammation with eosinophils. Ocular examination revealed multiple bilateral conjunctival granulomas. Conjunctival biopsies revealed granulomatous inflammation with plenty of eosinophils and flame figure configuration. Peripheral blood smear showed increased absolute eosinophil count and eosinophilia. Stool analysis was normal. She did not have abdominal symptoms or recurrence of granulomas. Conclusion: The rare association of bilateral conjunctival granulomas with hypereosinophilic syndrome has been described in this report.

Keywords: Bilateral; biopsy; conjunctival granulomas; eosinophilia; hypereosinophilia syndrome.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Conjunctival Diseases / etiology*
  • Female
  • Granuloma / etiology*
  • Humans
  • Hypereosinophilic Syndrome / complications*
  • Retrospective Studies