Abstract
Antibodies that potently neutralize highly diverse HIV-1 variants offer great potential for therapy and prevention. Passive administration of HIV-specific neutralizing antibodies genetically modified to have a long serum half-life has now been shown to confer long-lasting protection from infection in the rhesus macaque model.
MeSH terms
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Animals
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Antibodies, Neutralizing / administration & dosage*
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Antibodies, Neutralizing / pharmacology
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Antibodies, Viral / administration & dosage
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Antibodies, Viral / pharmacology
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Disease Models, Animal
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HIV Infections / prevention & control*
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HIV-1 / drug effects
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HIV-1 / immunology*
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HIV-1 / pathogenicity
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Half-Life
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Humans
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Macaca mulatta
Substances
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Antibodies, Neutralizing
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Antibodies, Viral