Bartonella henselae infection presenting as cervical spine osteomyelitis: case report

J Neurosurg Pediatr. 2018 Aug;22(2):189-194. doi: 10.3171/2018.2.PEDS17600. Epub 2018 May 25.

Abstract

Bartonella henselae is a gram-negative bacillus implicated in cat-scratch disease. Cat-scratch disease is usually self-limiting and results in local lymphadenopathy. In rare circumstances, patients may develop endocarditis, neuroretinitis, or osteomyelitis. Osteomyelitis of the cervical spine is exceedingly rare, especially in the pediatric population, and to date there have been only 4 previously reported cases of cervical spine osteomyelitis caused by B. henselae, all of which were treated surgically. In this article, the authors report the case of a 7-year-old boy who presented with neck swelling and was found to have a C2-4 paravertebral B. henselae abscess with osteomyelitis of C-3 and epidural extension. To the authors' knowledge, this represents the first case in the literature of a cervical spine B. henselae infection managed conservatively.

Keywords: Bartonella henselae; CRP = C-reactive protein; CSD = cat-scratch disease; ESR = erythrocyte sedimentation rate; PCR = polymerase chain reaction; WBC = white blood cell; cat-scratch disease; cervical spine; infection; lymphadenopathy; osteomyelitis.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Bartonella henselae / pathogenicity*
  • C-Reactive Protein / metabolism
  • Cat-Scratch Disease* / complications
  • Cat-Scratch Disease* / diagnostic imaging
  • Cat-Scratch Disease* / etiology
  • Cat-Scratch Disease* / microbiology
  • Cervical Cord / diagnostic imaging
  • Cervical Cord / pathology*
  • Child
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Osteomyelitis / diagnostic imaging
  • Osteomyelitis / etiology*
  • Osteomyelitis / microbiology
  • Tomography Scanners, X-Ray Computed

Substances

  • Anti-Bacterial Agents
  • C-Reactive Protein