The association of indwelling urinary catheter with delirium in hospitalized patients and nursing home residents: an explorative analysis from the "Delirium Day 2015"

Aging Clin Exp Res. 2019 Mar;31(3):411-420. doi: 10.1007/s40520-018-0974-1. Epub 2018 Jun 1.

Abstract

Backround: Use of indwelling urinary catheter (IUC) in older adults has negative consequences, including delirium.

Aim: This analysis, from the "Delirium Day 2015", a nationwide multicenter prevalence study, aim to evaluate the association of IUC with delirium in hospitalized and Nursing Homes (NHs) patients.

Methods: Patients underwent a comprehensive geriatric assessment, including the presence of IUC; inclusion criteria were age > 65 years, being Italian speaker and providing informed consent; exclusion criteria were coma, aphasia, end-of-life status. Delirium was assessed using the 4AT test (score ≥ 4: possible delirium; scores 1-3: possible cognitive impairment).

Results: Among 1867 hospitalized patients (mean age 82.0 ± 7.5 years, 58% female), 539 (28.9%) had IUC, 429 (22.9%) delirium and 675 (36.1%) cognitive impairment. IUC was significantly associated with cognitive impairment (OR 1.60, 95% CI 1.19-2.16) and delirium (2.45, 95% CI 1.73-3.47), this latter being significant also in the subset of patients without dementia (OR 2.28, 95% CI 1.52-3.43). Inattention and impaired alertness were also independently associated with IUC. Among 1454 NHs residents (mean age 84.4 ± 7.4 years, 70.% female), 63 (4.3%) had IUC, 535 (36.8%) a 4AT score ≥ 4, and 653 (44.9%) a 4AT score 1-3. The multivariate logistic regression analysis did not show a significant association between 4AT test or its specific items with IUC, neither in the subset of patients without dementia.

Discussion: We confirmed a significant association between IUC and delirium in hospitalized patients but not in NHs residents.

Conclusion: Environmental and clinical factors of acute setting might contribute to IUC-associated delirium occurrence.

Keywords: 4AT test; Cognition; Delirium; Geriatric assessment.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Catheters, Indwelling / adverse effects*
  • Delirium / etiology*
  • Female
  • Humans
  • Logistic Models
  • Male
  • Nursing Homes*
  • Urinary Catheterization / adverse effects*