Objective: To clarify the situation of the detection of upper gastrointestinal cancer and precancerous lesions in the Feicheng city and discuss the possible influencing factors. Methods: A cluster sampling method was used to determine the participants. A unified questionnaire was used to investigate the basic information including history of alcohol intake, smoking and chinese tea, as well as other eating habits, medical history of digestive tract and cancer. Endoscopy was used to to screen the patients with upper gastrointestinal cancer and precancerous lesions. Influential factors were explored by non-conditional logistic regression model. Results: 911 of 7 291participants were positive, and the total detection rate was 12.49%. The total positive detection rate of male and female was 17.94% and 8.71%, respectively (P<0.001). Multivariate logistic regression analysis showed that the sex (OR=0.527, 95%CI: 0.440-0.631), age (OR=2.037, 95%CI: 1.849-2.245), smoking (OR=1.240, 95%CI: 1.014-1.516) and alcohol consumption (OR=1.232, 95%CI: 1.012-1.500) , meat and protein intake (OR=0.794, 95%CI: 0.638-0.987) and drink tea (OR=1.233, 95%CI: 1.056-1.440) may be influencing factors of the total detection rate of upper gastrointestinal cancer and precancerosis. Conclusions: In Feicheng city, intake of meat and protein is the protective factor of the upper gastrointestinal cancer and precancerous lesions. Men, aged, smoking, drinking and tea will increase the risk of upper gastrointestinal cancer and precancerous lesions.
目的：明确肥城市上消化道癌及癌前病变的总检出情况，探讨其影响因素。 方法：采用整群抽样方法确定调查对象。采用统一调查问卷，调查其基本信息，主要包括饮酒、吸烟以及饮茶等饮食、行为习惯，消化道病史以及肿瘤家族史。采用内镜检查对调查对象进行上消化道癌及癌前病变筛查。影响因素分析采用非条件Logistic回归模型分析。 结果： 7 291名筛查对象中，共检出阳性病例911例，总阳性检出率为12.49%。男性阳性检出率为17.94%，女性阳性检出率为8.71%，差异有统计学意义(P<0.001)。多因素Logistic回归分析显示，性别(OR＝0.527，95%CI：0.440～0.631)、年龄(OR＝2.037，95%CI：1.849～2.245)、吸烟(OR＝1.240，95%CI：1.014～1.516)、饮酒(OR＝1.232，95%CI：1.012～1.500)、肉蛋奶摄入(OR＝0.794，95%CI：0.638～0.987)和饮花茶(OR＝1.233，95%CI：1.056～1.440)是上消化道癌及癌前病变发生的独立影响因素。 结论：在肥城市居民中，男性、年龄大、吸烟、饮酒和饮花茶会增加发生上消化道癌及癌前病变的风险，肉蛋奶的摄入是上消化道癌及癌前病变的保护因素。.
Keywords: Influencing factors; Neoplasms; Precancerous conditions; Screening; Upper gastrointestinal.