Depression and Quality of Life in Siblings of Children With Cancer After Group Intervention Participation: A Randomized Control Trial

J Pediatr Psychol. 2018 Nov 1;43(10):1093-1103. doi: 10.1093/jpepsy/jsy040.

Abstract

Objective: The objective of this study was to (1) assess the effects of a group intervention called Siblings Coping Together on siblings' psychosocial adjustment compared with controls; (2) explore the potential moderating effect of siblings' gender; and (3) investigate whether the intervention was more effective for siblings with more depressive symptoms at baseline.

Methods: This was a repeated measure, parallel randomized controlled trial (RCT) with two groups. Seventy-five healthy siblings (7-16 years old, 41 males) participated. Both groups had 8 weekly 2-hr sessions. Intervention sessions had psychoeducational, social, and therapeutic problem-solving goals taught through games and crafts (n = 41); controls (n = 34) had games and crafts only. Self-reported symptoms of depression (Children's Depression Inventory, CDI) and self- and proxy-reported quality of life (QOL) (Pediatric Quality of Life Inventory, PedsQL) were obtained at baseline, postintervention, and 3 months later. Multivariable analyses with a mixed effects model were performed.

Results: No significant main group effect or group × time interactions were found for any of the scales assessed. Significant improvement over time was found for total CDI (p < .01) and proxy-reported PedsQL total (p < .001) in both groups, which may have been attributable to the passage of time.

Conclusions: No sufficient evidence was obtained for the efficacy of the intervention in the current study. Future research may examine conducting a larger RCT comparing sibling support group to no treatment control group.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptation, Psychological
  • Adolescent
  • Canada
  • Child
  • Depressive Disorder / psychology*
  • Depressive Disorder / therapy*
  • Female
  • Humans
  • Male
  • Neoplasms / psychology*
  • Psychotherapy, Group / methods*
  • Quality of Life / psychology*
  • Severity of Illness Index
  • Sex Factors
  • Siblings / psychology*
  • Treatment Outcome