Economic burden of patients with diffuse large B-cell and follicular lymphoma treated in the USA

Future Oncol. 2018 Oct;14(25):2627-2642. doi: 10.2217/fon-2018-0267. Epub 2018 Jun 18.

Abstract

Aim: Evaluate healthcare costs and utilization of treated diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL) patients.

Materials & methods: Adults with newly diagnosed DLBCL and FL between 1 January 2008 and 31 October 2015 were identified in the Optumâ„¢ claims database. Healthcare costs and utilization were assessed from diagnosis date until end of follow-up.

Results: A total of 1267 DLBCL- and 1595 FL-treated patients were identified. Mean per-patient, per-month cost during follow-up was US$11,890 for DLBCL and US$10,460 for FL. Healthcare costs and utilization decreased from year 1 to 2 following diagnosis, due to a decrease in chemotherapy services, inpatient admissions and other outpatient services.

Conclusion: The economic burden of treated DLBCL and FL is considerable, especially in the first year following diagnosis.

Keywords: cost; diffuse large B-cell lymphoma; economic burden; follicular lymphoma; healthcare utilization; real-world; retrospective; treatment.

Publication types

  • Observational Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Cost of Illness*
  • Female
  • Health Care Costs
  • Humans
  • Inpatients
  • Lymphoma, Follicular / economics*
  • Lymphoma, Follicular / therapy
  • Lymphoma, Large B-Cell, Diffuse / economics*
  • Lymphoma, Large B-Cell, Diffuse / therapy
  • Male
  • Middle Aged
  • Retrospective Studies
  • United States
  • Young Adult