[The importance of molecular imaging (PET) in the diagnostics of dementia]

Nervenarzt. 2018 Jul;89(7):843-856. doi: 10.1007/s00115-018-0533-1.
[Article in German]

Abstract

Due to the expanding older population and increasing prevalence of dementia and currently lacking curative therapy but potentially conceivable availability of molecular-specific treatment to delay the progression of cognitive decline, the early diagnosis of cognitive deficits and their etiological differential diagnosis becomes increasingly more important. The advances in nuclear medicine diagnostics in the field of neurodegenerative diseases within the last few years have been substantial. In this article the relevance of these technologies in the diagnostic process of dementia is described.

Keywords: Alzheimer’s disease; Amyloid/Tau; Nuclear medicine diagnostics; Positron emission tomography; Progression delay.

MeSH terms

  • Alzheimer Disease / diagnostic imaging
  • Cognitive Dysfunction / diagnostic imaging
  • Dementia* / classification
  • Dementia* / diagnostic imaging
  • Humans
  • Positron-Emission Tomography*