[Bridging anticoagulation in patients receiving vitamin K antagonists : Current status]

Anaesthesist. 2018 Aug;67(8):599-606. doi: 10.1007/s00101-018-0463-0.
[Article in German]

Abstract

Approximately 30% of patients receiving oral anticoagulation using vitamin K antagonists (VKA) require surgery within 2 years. In this context, a clinical decision on the need and the mode of a peri-interventional bridging with heparin is needed. While a few years ago, bridging was almost considered a standard of care, recent study results triggered a discussion on which patients will need bridging at all. Revisiting the currently available recommendations and study results the conclusion can be drawn that the indications for bridging with heparin must nowadays be taken more narrowly and considering the individual patient risk of bleeding and thromboembolism. Bridging with heparin is only needed in patients with a very high risk of thromboembolism. This overview aims to give guidance for a risk-adapted peri-interventional approach to management of patients with a need for long-term anticoagulation using VKA.

Keywords: Heparin, low molecular weight; International Normalized Ratio; Perioperative care; Risk, hemorrhage; Risk, thromboembolism.

Publication types

  • Review

MeSH terms

  • Anticoagulants / therapeutic use*
  • Blood Coagulation / drug effects
  • Fibrinolytic Agents / therapeutic use*
  • Hemorrhage / chemically induced
  • Heparin / therapeutic use*
  • Humans
  • Thrombolytic Therapy / methods
  • Vitamin K / antagonists & inhibitors*

Substances

  • Anticoagulants
  • Fibrinolytic Agents
  • Vitamin K
  • Heparin