Racial Differences in the Anatomy of the Posterior Fossa: Neurosurgical Considerations

World Neurosurg. 2018 Sep:117:e571-e574. doi: 10.1016/j.wneu.2018.06.089. Epub 2018 Jun 20.

Abstract

Objective: Racial differences in anatomy of the cranium exist but have not been specifically considered in neurosurgical access planning. We sought to find differences in the anatomy of the posterior fossa in a cohort study consisting of Asian, African American, and Caucasian patients.

Methods: Magnetic resonance imaging data of 60 Asian, 57 African American, and 70 Caucasian individuals were obtained from the Human Connectome Project. Measurements were done in axial, coronal, and sagittal planes in T2-weighted thin-sliced images. P values were calculated using 2-tailed Student t test. P < 0.05 was considered significant.

Results: We measured distance in millimeters from the z values (craniocaudal axis) from the internal acoustic meatus to the transition of the transverse sinus into the sigmoid sinus. We discovered significant differences across all races. Our results show that the junction of the transverse to sigmoid sinus is lowest in Caucasians followed by Asians and African Americans.

Conclusions: Significant differences in anatomy have practical implications in the retrosigmoid approach to the cerebellopontine angle. Based on our findings, the junction of the transverse sinus with the sigmoid sinus can differ up to 0.5 cm in the craniocaudal axis depending on race. As neuronavigation is not standard to the approach to the cerebellopontine angle, the study aimed to provide the neurosurgeon operating in the retrosigmoid area additional knowledge to avoid sinus injury with subsequent complications, such as blood loss, sinus occlusion, or air embolism.

Keywords: Cerebellopontine angle; Neuroanatomy; Race; Retrosigmoid approach; Vestibular schwannoma.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Asian People*
  • Biological Variation, Individual
  • Black or African American*
  • Cohort Studies
  • Cranial Fossa, Posterior / anatomy & histology*
  • Cranial Fossa, Posterior / diagnostic imaging*
  • Cranial Fossa, Posterior / surgery
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Neurosurgical Procedures
  • Organ Size
  • White People*
  • Young Adult