Diplotype analysis of NUDT15 variants and 6-mercaptopurine sensitivity in pediatric lymphoid neoplasms

Leukemia. 2018 Dec;32(12):2710-2714. doi: 10.1038/s41375-018-0190-1. Epub 2018 Jul 2.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Female
  • Genetic Variation / genetics*
  • Humans
  • Infant
  • Leukemia, Lymphoid / drug therapy*
  • Leukemia, Lymphoid / genetics*
  • Male
  • Mercaptopurine / therapeutic use*
  • Pyrophosphatases / genetics*
  • Young Adult

Substances

  • Mercaptopurine
  • NUDT15 protein, human
  • Pyrophosphatases