Muscling in on the Awesome Proliferative Power of the Terrible Teratoma

Alicia A Cutler; Bradley B Olwin

doi:10.1016/j.stem.2018.06.011

Muscling in on the Awesome Proliferative Power of the Terrible Teratoma

Cell Stem Cell. 2018 Jul 5;23(1):1-2. doi: 10.1016/j.stem.2018.06.011.

Authors

Alicia A Cutler¹, Bradley B Olwin²

Affiliations

¹ Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO, USA.
² Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO, USA. Electronic address: olwin@colorado.edu.

PMID: 29979984
DOI: 10.1016/j.stem.2018.06.011

Abstract

In this issue of Cell Stem Cell, Chan et al. (2018) report that in vivo differentiation of pluripotent stem cells in induced teratomas produces functional embryonic-like muscle stem cells. These purified muscle stem cells engraft with high efficiency and regenerate serially injured muscle.

Publication types

Comment

MeSH terms

Cell Differentiation
Humans
Muscle Fibers, Skeletal
Myoblasts
Pluripotent Stem Cells*
Teratoma*

Grants and funding

R01 AR049446/AR/NIAMS NIH HHS/United States