Exceptional Response to Cabozantinib of Rapidly Evolving Brain Metastases of Renal Cell Carcinoma: A Case Report and Review of the Literature

Clin Genitourin Cancer. 2018 Oct;16(5):e1069-e1071. doi: 10.1016/j.clgc.2018.06.005. Epub 2018 Jun 21.
No abstract available

Keywords: Antiangiogenic targeted agents; Blood–brain barrier penetration; Brain metastases; Complete response; RCC.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Anilides / therapeutic use*
  • Brain Neoplasms / diagnostic imaging
  • Brain Neoplasms / drug therapy*
  • Brain Neoplasms / secondary
  • Carcinoma, Renal Cell / diagnostic imaging
  • Carcinoma, Renal Cell / drug therapy*
  • Carcinoma, Renal Cell / secondary
  • Female
  • Humans
  • Indazoles
  • Kidney Neoplasms / diagnostic imaging
  • Kidney Neoplasms / drug therapy*
  • Kidney Neoplasms / pathology
  • Magnetic Resonance Imaging
  • Middle Aged
  • Protein Kinase Inhibitors / therapeutic use*
  • Pyridines / therapeutic use*
  • Pyrimidines / therapeutic use
  • Sulfonamides / therapeutic use
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Anilides
  • Indazoles
  • Protein Kinase Inhibitors
  • Pyridines
  • Pyrimidines
  • Sulfonamides
  • cabozantinib
  • pazopanib