A Feasibility Study Utilizing the Thulium and Holmium Laser in Patients for the Treatment of Recurrent Benign Prostatic Hyperplasia after Previous Prostatic Surgery

Urol Int. 2018;101(2):212-218. doi: 10.1159/000489858. Epub 2018 Jul 17.

Abstract

Background: Transurethral resection of the prostate (TURP) is considered to be the standard treatment for patients with benign prostatic obstruction (BPO) ≤80 mL. However, up to 14.7% of the patients require secondary TURP due to recurrent BPO. The aim of our study was to describe specific features of holmium laser enucleation of the prostate (HoLEP) and thulium laser enucleation of the prostate (ThuLEP) in patients with recurrent BPO after previous prostate surgery.

Materials and methods: A total of 768 consecutive patients from our prospective collected database were retrospectively reviewed and divided into 4 groups: group A (489 patients) and group C (253 patients) underwent primary HoLEP and ThuLEP treatment, while group B (17 patients) and D (9 patients) included patients with recurrent BPO who were treated with HoLEP and ThuLEP, respectively.

Results: There were no significant differences in preoperative parameters between the groups at primary (A and C) and secondary (B and D) treatment except their age. At 6-month follow-up, voiding parameters and symptom scores showed statistically significant improvements compared to baseline without differences between the groups. The mean operative time was comparable between the groups and did not differ significantly (p > 0.05).

Conclusions: Laser enucleation for the treatment of recurrent BPO is feasible and seems to be a safe and effective procedure.

Keywords: Benign prostatic obstruction; Endoscopic laser enucleation; Recurrent adenoma.

MeSH terms

  • Aged
  • Databases, Factual
  • Feasibility Studies
  • Humans
  • Laser Therapy / adverse effects
  • Laser Therapy / instrumentation*
  • Lasers, Solid-State / adverse effects
  • Lasers, Solid-State / therapeutic use*
  • Male
  • Middle Aged
  • Prostatic Hyperplasia / diagnosis
  • Prostatic Hyperplasia / physiopathology
  • Prostatic Hyperplasia / surgery*
  • Recurrence
  • Retrospective Studies
  • Thulium / adverse effects
  • Thulium / therapeutic use*
  • Transurethral Resection of Prostate* / adverse effects
  • Treatment Outcome

Substances

  • Thulium