Epidemiology, clinical and laboratory features of 24 consecutive cases of leptospirosis at a German infectious disease center

Infection. 2018 Dec;46(6):847-853. doi: 10.1007/s15010-018-1181-x. Epub 2018 Jul 17.

Abstract

To determine epidemiological, clinical and laboratory characteristics of leptospirosis, 24 consecutive patients diagnosed with the infection between 2011 and 2017 at the University Medical Center Hamburg-Eppendorf were retrospectively analyzed. The majority of patients were male travelers who returned from Southeast Asia and had a history of freshwater-associated activities. Considering the lack of discriminatory clinical or clinical chemistry parameters, leptospirosis should be regarded as differential diagnosis in any patient with acute febrile illness, especially with a history of travel to tropical and subtropical regions or freshwater exposure.

Keywords: Germany; Leptospirosis; Southeast Asia; Traveler; Zoonosis.

MeSH terms

  • Adult
  • Aged
  • Asia, Southeastern
  • Cohort Studies
  • Communicable Diseases, Imported / diagnosis*
  • Communicable Diseases, Imported / epidemiology*
  • Communicable Diseases, Imported / microbiology
  • Diagnosis, Differential
  • Female
  • Fever / diagnosis*
  • Germany / epidemiology
  • Humans
  • Leptospirosis / diagnosis*
  • Leptospirosis / epidemiology*
  • Leptospirosis / microbiology
  • Male
  • Middle Aged
  • Retrospective Studies
  • Travel
  • Tropical Climate
  • Young Adult