Orofacial granulomatosis and erythema multiforme in an adolescent with Crohn's disease

Pediatr Dermatol. 2018 Sep;35(5):e294-e297. doi: 10.1111/pde.13548. Epub 2018 Jun 26.

Abstract

The cutaneous manifestations of Crohn's disease are myriad. A 15-year-old girl presented with recurrent lip swelling and eventual development of diarrhea and targetoid macules on the palms, feet, and back. She was finally diagnosed with Crohn's disease in the setting of a clinical presentation and histopathology consistent with orofacial granulomatosis and erythema multiforme. We review the literature and summarize reported occurrences of these cutaneous diseases in children with Crohn's disease.

Keywords: Crohn's disease; erythema multiforme; inflammatory bowel disease; orofacial granulomatosis.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Crohn Disease / complications
  • Crohn Disease / diagnosis*
  • Crohn Disease / drug therapy
  • Erythema Multiforme / complications*
  • Female
  • Glucocorticoids / therapeutic use
  • Granulomatosis, Orofacial / complications
  • Granulomatosis, Orofacial / diagnosis*
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Skin / pathology

Substances

  • Glucocorticoids
  • Immunosuppressive Agents