Non-internal tandem duplication (ITD), non-tyrosine kinase domain (TKD) FLT3 mutations in myeloid malignancies: A brief report of 10 patients

Leuk Res. 2018 Sep:72:1-4. doi: 10.1016/j.leukres.2018.07.018. Epub 2018 Jul 21.

Authors

Alexandra Higgins¹, Abhishek A Mangaonkar², Mehrdad Hefazi², David Viswanatha³, Pedro Horna³, James Foran⁴, Naseema Gangat⁵

Affiliations

¹ Department of Internal Medicine, Mayo Clinic, Rochester MN, United States.
² Division of Hematology, Mayo Clinic, Rochester MN, United States.
³ Department of Pathology, Mayo Clinic, Rochester MN, United States.
⁴ Department of Hematology & Medical Oncology, Mayo Clinic, Jacksonville FL, United States.
⁵ Division of Hematology, Mayo Clinic, Rochester MN, United States. Electronic address: gangat.naseema@mayo.edu.

PMID: 30055376
DOI: 10.1016/j.leukres.2018.07.018

No abstract available

Publication types

Clinical Trial
Letter

MeSH terms

Adult
Aged
Aged, 80 and over
Female
Hematologic Neoplasms / enzymology
Hematologic Neoplasms / genetics*
Hematologic Neoplasms / pathology
Humans
Male
Middle Aged
Mutation*
Myeloproliferative Disorders / enzymology
Myeloproliferative Disorders / genetics*
Myeloproliferative Disorders / pathology
Protein Domains
fms-Like Tyrosine Kinase 3 / genetics*

Substances

FLT3 protein, human
fms-Like Tyrosine Kinase 3