Pediatric Brain Tumors

Yoko T Udaka; Roger J Packer

doi:10.1016/j.ncl.2018.04.009

Pediatric Brain Tumors

Neurol Clin. 2018 Aug;36(3):533-556. doi: 10.1016/j.ncl.2018.04.009.

Authors

Yoko T Udaka¹, Roger J Packer²

Affiliations

¹ The Brain Tumor Institute, Center for Neuroscience and Behavioral Medicine, Children's National Health System, 111 Michigan Avenue Northwest, Washington, DC 20010, USA; Division of Oncology, Center for Cancer and Blood Disorders, 111 Michigan Avenue Northwest, Washington, DC 20010, USA.
² The Brain Tumor Institute, Center for Neuroscience and Behavioral Medicine, Children's National Health System, 111 Michigan Avenue Northwest, Washington, DC 20010, USA; The Brain Tumor Institute, Gilbert Family Neurofibromatosis Institute, Children's National Medical Center, 111 Michigan Avenue Northwest, Washington, DC 20010, USA. Electronic address: RPacker@childrensnational.org.

PMID: 30072070
DOI: 10.1016/j.ncl.2018.04.009

Abstract

Pediatric central nervous system (CNS) tumors are the most common solid tumors in children and comprise 15% to 20% of all malignancies in children. Presentation, symptoms, and signs depend on tumor location and age of the patient at the time of diagnosis. This article summarizes the common childhood CNS tumors, presentations, classification, and recent updates in treatment approaches due to the increased understanding of the molecular pathogenesis of pediatric brain tumors.

Keywords: Brain tumors; Embryonal tumors; Gliomas; Medulloblastoma; Pediatric brain tumors.

Publication types

Review

MeSH terms

Adolescent
Brain Neoplasms / epidemiology*
Brain Neoplasms / pathology*
Brain Neoplasms / therapy
Cerebellar Neoplasms / epidemiology
Cerebellar Neoplasms / pathology
Cerebellar Neoplasms / therapy
Child
Child, Preschool
Female
Glioma / epidemiology
Glioma / pathology
Glioma / therapy
Humans
Infant
Infant, Newborn
Male
Rhabdoid Tumor / epidemiology
Rhabdoid Tumor / pathology
Rhabdoid Tumor / therapy
Teratoma / epidemiology
Teratoma / pathology
Teratoma / therapy

Supplementary concepts

Typical Teratoid Rhabdoid Tumor