Reply to Haffner et al.: DNA hypomethylation renders tumors more immunogenic
Proc Natl Acad Sci U S A
.
2018 Sep 11;115(37):E8583-E8584.
doi: 10.1073/pnas.1811015115.
Epub 2018 Sep 4.
Authors
Meredith L Stone
1
,
Katherine B Chiappinelli
1
,
Huili Li
1
,
Lauren M Murphy
1
,
Meghan E Travers
1
,
Michael J Topper
1
,
Dimitrios Mathios
2
,
Michael Lim
2
,
Ie-Ming Shih
3
,
Tian-Li Wang
4
,
Chien-Fu Hung
4
,
Vipul Bhargava
5
,
Karla R Wiehagen
6
,
Glenn S Cowley
5
,
Kurtis E Bachman
7
,
Reiner Strick
8
,
Pamela L Strissel
8
,
Stephen B Baylin
9
,
Cynthia A Zahnow
9
Affiliations
1
Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287.
2
Department of Neurosurgery, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287.
3
Department of Gynecology and Obstetrics, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287.
4
Department of Pathology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287.
5
Discovery Sciences, Janssen Research & Development, Spring House, PA 19477.
6
Immuno-Oncology Discovery, Janssen Research & Development, Spring House, PA 19477.
7
Oncology Janssen Research & Development, Spring House, PA 19477.
8
Laboratory for Molecular Medicine, Department of Gynaecology and Obstetrics, University-Clinic Erlangen, 91054 Erlangen, Germany.
9
Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287; zahnoci@jhmi.edu sbaylin@jhmi.edu.
PMID:
30181297
PMCID:
PMC6140504
DOI:
10.1073/pnas.1811015115
No abstract available
Publication types
Letter
Comment
MeSH terms
DNA
DNA Methylation*
Humans
Neoplasms*
Substances
DNA
Grants and funding
R00 CA204592/CA/NCI NIH HHS/United States
T32 GM008752/GM/NIGMS NIH HHS/United States