Applications of PET/CT and PET/MR Imaging in Primary Bone Malignancies

PET Clin. 2018 Oct;13(4):623-634. doi: 10.1016/j.cpet.2018.05.012. Epub 2018 Aug 17.

Abstract

Primary bone malignancies are characterized with anatomic imaging. However, in recent years, there has been an increased interest in PET/computed tomography scanning and PET/MRI with fludeoxyglucose F 18 for evaluating and staging musculoskeletal neoplasms. These hybrid imaging modalities have shown promise largely owing to their high sensitivity, ability to perform more thorough staging, and ability to monitor treatment response. This article reviews the current role of PET/computed tomography scanning and PET/MRI in primary malignancies of bone, with an emphasis on imaging characteristics, clinical usefulness, and current limitations.

Keywords: PET/CT; PET/MRI; Primary bone malignancies.

Publication types

  • Review

MeSH terms

  • Adult
  • Aged
  • Bone Neoplasms / pathology*
  • Chondrosarcoma / pathology
  • Female
  • Fluorodeoxyglucose F18
  • Giant Cell Tumor of Bone / pathology
  • Humans
  • Lymphoma / pathology
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Multimodal Imaging / methods
  • Multiple Myeloma / pathology
  • Osteosarcoma / pathology
  • Positron Emission Tomography Computed Tomography / methods
  • Positron-Emission Tomography / methods*
  • Radiopharmaceuticals
  • Sarcoma, Ewing / pathology
  • Young Adult

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18