Blood Pressure Variability in Acute Ischemic Stroke: The Role of Early Recanalization

Eur Neurol. 2018;80(1-2):63-67. doi: 10.1159/000492627. Epub 2018 Sep 18.

Abstract

We performed a retrospective study with the aim of investigating the association between blood pressure (BP) variability in the first 24 h after ischemic stroke and functional outcome, regarding arterial recanalization status. A total of 674 patients diagnosed with acute stroke and treated with revascularization therapies were enrolled. Systolic and diastolic BP values of the first 24 h after stroke were collected and their variation quantified through standard deviation. Recanalization state was evaluated at 6 h and clinical outcome at 3 months was assessed by modified Rankin Scale. In multivariate analyses systolic BP variability in the first 24 h post-stroke showed an association with 3 months clinical outcome in the whole population and non-recanalyzed patients. In recanalyzed patients, BP variability did not show a significant association with functional outcome.

Keywords: Acute stroke; Blood pressure fluctuations; Recanalization.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Blood Pressure / physiology*
  • Brain Ischemia / physiopathology
  • Brain Ischemia / therapy
  • Endovascular Procedures / methods*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Recovery of Function
  • Retrospective Studies
  • Stroke / physiopathology*
  • Stroke / therapy*
  • Treatment Outcome*