Latent Class Analysis of Specialized Palliative Care Needs in Adult Intensive Care Units From a Single Academic Medical Center

J Pain Symptom Manage. 2019 Jan;57(1):73-78. doi: 10.1016/j.jpainsymman.2018.10.270. Epub 2018 Oct 11.

Abstract

Context: In the intensive care unit (ICU), 14% of patients meet criteria for specialized palliative care, but whether subgroups of patients differ in their palliative care needs is unknown.

Objectives: The objective of this study was to use latent class analysis to separate ICU patients into different classes of palliative care needs and determine if such classes differ in their palliative care resource requirements.

Methods: We conducted a retrospective cohort study of ICU patients who received specialized palliative care, August 2013 to August 2015. Reason(s) for consultation were extracted from the initial note and entered into a latent class analysis model to generate mutually exclusive patient classes. Differences in "high use" of palliative care (defined as having five or more palliative care visits) between classes were assessed using logistic regression, adjusting for age, race, Charlson Comorbidity Index, and length of stay.

Results: In a sample of 689 patients, a four-class model provided the most meaningful groupings: 1) Pain and Symptom Management (n = 218, 31.6%), 2) Goals of Care and Advance Directives (GCAD) (n = 131, 19.0%), 3) All Needs (n = 112, 16.3%), and 4) Supportive Care (n = 228, 33.1%). In comparison to GCAD patients, all other classes were more likely to require "high use" of palliative care (adjusted odds ratio [aOR] 2.61 [1.41-4.83] for "All Needs," aOR 2.01 [1.16-3.50] for "Pain and Symptom Management," aOR 1.94 [1.12-3.34] for "Supportive Care").

Conclusion: Based on the initial reason for consultation, we identified four classes of palliative care needs among critically ill patients, and GCAD patients were least likely to be high utilizers. These findings may help inform allocation of palliative care resources for this population.

Keywords: Palliative care; advance directives; critical illness; intensive care units; pain management; referral and consultation.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Academic Medical Centers
  • Adult
  • Advance Directives
  • Aged
  • Critical Care
  • Female
  • Humans
  • Intensive Care Units*
  • Latent Class Analysis
  • Male
  • Pain Management
  • Palliative Care* / classification
  • Referral and Consultation
  • Retrospective Studies