Long QT syndrome masquerading as epilepsy

Pract Neurol. 2019 Feb;19(1):56-61. doi: 10.1136/practneurol-2018-001959. Epub 2018 Oct 15.

Abstract

The diagnosis of epilepsy is incorrect in up to 20% of cases so should be revisited if attacks are not responding to treatment. We present a case of long QT syndrome that remained undiagnosed in the epilepsy clinic for 15 years until a near-fatal arrhythmia revealed the diagnosis and allowed effective treatment of her attacks. We hope this near miss raises awareness of long QT syndrome as a potentially fatal, rare but treatable condition that neurologists must consider in people with a label of refractory epilepsy. We provide practical pointers to increase the chance of early diagnosis and explore the impact of a late diagnosis for the patient and her family.

Keywords: anticonvulsants; cardiology; channels; epilepsy.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Diagnostic Errors*
  • Epilepsy / diagnosis*
  • Female
  • Humans
  • Long QT Syndrome / complications
  • Long QT Syndrome / diagnosis*
  • Seizures / etiology
  • Syncope / etiology
  • Young Adult