Pure Testicular Choriocarcinoma with Dermatological, Brain, and Gastrointestinal Metastases

Rama Nassri; Mayssan Muftah; Ammar Nassri; Ahmad Alkhasawneh; Jadranko Corak

doi:10.7759/cureus.3083

Pure Testicular Choriocarcinoma with Dermatological, Brain, and Gastrointestinal Metastases

Cureus. 2018 Aug 1;10(8):e3083. doi: 10.7759/cureus.3083.

Authors

Rama Nassri¹, Mayssan Muftah², Ammar Nassri³, Ahmad Alkhasawneh⁴, Jadranko Corak⁵

Affiliations

¹ Department of Medicine, Alfaisal University School of Medicine, Dhahran, SAU.
² Department of Internal Medicine, Emory University School of Medicine, Atlanta , USA.
³ Department of Medicine, University of Florida-Jacksonville, Jacksonville, USA.
⁴ Department of Pathology, University of Florida College of Medicine-Jacksonville, Jacksonville, USA.
⁵ Department of Internal Medicine, Dell Seton Medical Center at The University of Texas, Austin, USA.

Abstract

Testicular choriocarcinoma is a non-seminomatous germ cell tumor (NSGCT) and is the rarest of all testicular cancers. Nearly all choriocarcinomas can be classified as either pure choriocarcinoma or as a component of a mixed germ cell tumor. Pure testicular choriocarcinoma is extremely aggressive and metastasizes early and extensively. We present a case of testicular cancer that metastasized to the skin, gastrointestinal tract, and brain, and discuss the case in light of the available literature.

Keywords: brain metastases; dermatological metastases; gastrointestinal metastases; germ cell tumor; pure choriocarcinoma; testicular cancer.

Publication types

Case Reports