Among students with influenza-like illness at a Pennsylvania college student health center during 2016-2017, 44 (15%) of 288 with respiratory specimens tested positive for human adenovirus (HAdV). HAdV-3, -7, and -4 predominated, and types clustered temporally. HAdV infection should be considered among college students with acute respiratory illness.
Keywords: Pennsylvania; United States; adenovirus vaccines; epidemiology; human adenovirus infections; human adenoviruses; influenza-like illness; public health surveillance; respiratory infections; student health services; students; viruses.