Novel Multidrug-Resistant Cronobacter sakazakii Causing Meningitis in Neonate, China, 2015

Emerg Infect Dis. 2018 Nov;24(11):2121-2124. doi: 10.3201/eid2411.180718.

Abstract

We report a case of meningitis in a neonate in China, which was caused by a novel multidrug-resistant Cronobacter sakazakii strain, sequence type 256, capsular profile K1:CA1. We identified genetic factors associated with bacterial pathogenicity and antimicrobial drug resistance in the genome and plasmids. Enhanced surveillance of this organism is warranted.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Cronobacter sakazakii / genetics*
  • Cronobacter sakazakii / pathogenicity
  • Drug Resistance, Multiple, Bacterial / genetics*
  • Enterobacteriaceae Infections / diagnosis
  • Enterobacteriaceae Infections / epidemiology
  • Enterobacteriaceae Infections / microbiology*
  • Genome, Bacterial / genetics*
  • Humans
  • Infant, Newborn
  • Meningitis / diagnosis*
  • Meningitis / epidemiology
  • Meningitis / microbiology
  • Plasmids / genetics

Substances

  • Anti-Bacterial Agents