Return of secondary findings in genomic sequencing: Military implications

Mol Genet Genomic Med. 2019 Feb;7(2):e00483. doi: 10.1002/mgg3.483. Epub 2018 Nov 10.

Abstract

Background: Genomic sequencing has become a widely used tool in clinical and research settings in both civilian and military healthcare systems.

Methods: In this paper, we consider potential military-specific implications of returning genomic sequencing secondary findings to ensure the proper protections, policies, and processes are in place for the use of this information.

Results: We specifically use two examples to highlight potential military implications of the return of secondary findings.

Conclusion: Clinicians and researchers are strongly encouraged to consider the military implications of the return of results for informed consent of service members or their families undergoing clinical or research genomic sequencing.

Keywords: genomics; military; secondary findings.

Publication types

  • Review

MeSH terms

  • Arrhythmogenic Right Ventricular Dysplasia / genetics*
  • Genetic Carrier Screening / standards*
  • Genetic Counseling / standards*
  • Humans
  • Incidental Findings*
  • Informed Consent
  • Malignant Hyperthermia / genetics*
  • Military Medicine / standards*
  • Military Personnel*
  • Whole Genome Sequencing / standards*