Exposure to Household Air Pollution from Biomass Cookstoves and Levels of Fractional Exhaled Nitric Oxide (FeNO) among Honduran Women

Megan L Benka-Coker; Maggie L Clark; Sarah Rajkumar; Bonnie N Young; Annette M Bachand; John R Balmes; Robert Brook; Tracy L Nelson; John Volckens; Steve J Reynolds; Ander Wilson; Christian L'Orange; Nicholas Good; Casey Quinn; Kirsten Koehler; Sebastian Africano; Anibal Osorto Pinel; Jennifer L Peel

doi:10.3390/ijerph15112544

Exposure to Household Air Pollution from Biomass Cookstoves and Levels of Fractional Exhaled Nitric Oxide (FeNO) among Honduran Women

Int J Environ Res Public Health. 2018 Nov 13;15(11):2544. doi: 10.3390/ijerph15112544.

Authors

Megan L Benka-Coker^{1

2}, Maggie L Clark³, Sarah Rajkumar⁴, Bonnie N Young⁵, Annette M Bachand⁶, John R Balmes⁷, Robert Brook⁸, Tracy L Nelson⁹, John Volckens^{10

11}, Steve J Reynolds¹², Ander Wilson¹³, Christian L'Orange¹⁴, Nicholas Good¹⁵, Casey Quinn¹⁶, Kirsten Koehler¹⁷, Sebastian Africano¹⁸, Anibal Osorto Pinel^{19

20}, Jennifer L Peel²¹

Affiliations

¹ Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA. mbenka@gettysburg.edu.
² Department of Health Sciences, Gettysburg College, Gettysburg, PA 17325, USA. mbenka@gettysburg.edu.
³ Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA. maggie.clark@colostate.edu.
⁴ Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA. sarah.rajkumar@yahoo.de.
⁵ Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA. bonnie.young@colostate.edu.
⁶ Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA. abachand@ramboll.com.
⁷ Division of Occupational and Environmental Medicine, University of California, San Francisco, San Francisco, CA 94143, USA. john.balmes@ucsf.edu.
⁸ Division of Cardiovascular Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA. robdbrok@med.umich.edu.
⁹ Department of Health and Exercise Science, Colorado State University, Fort Collins, CO 80523, USA. tracy.nelson@colostate.edu.
¹⁰ Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA. john.volckens@colostate.edu.
¹¹ Department of Mechanical Engineering, Colorado State University, Fort Collins, CO 80523, USA. john.volckens@colostate.edu.
¹² Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA. stephen.reynolds@colostate.edu.
¹³ Department of Statistics, Colorado State University, Fort Collins, CO 80523, USA. ander.wilson@colostate.edu.
¹⁴ Department of Mechanical Engineering, Colorado State University, Fort Collins, CO 80523, USA. christian.lorange@colostate.edu.
¹⁵ Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA. n.good@colostate.edu.
¹⁶ Department of Mechanical Engineering, Colorado State University, Fort Collins, CO 80523, USA. casey.quinn@colostate.edu.
¹⁷ Department of Environmental Health and Engineering, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA. kkoehle1@jhu.edu.
¹⁸ Trees, Water & People, Fort Collins, CO 80524, USA. sebastian@treeswaterpeople.org.
¹⁹ Trees, Water & People, Fort Collins, CO 80524, USA. anibalosorto@yahoo.es.
²⁰ Asociación Hondureña para el Desarrollo, Tegucigalpa, MDC, Honduras. anibalosorto@yahoo.es.
²¹ Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA. jennifer.peel@colostate.edu.

Abstract

Household air pollution is estimated to be responsible for nearly three million premature deaths annually. Measuring fractional exhaled nitric oxide (FeNO) may improve the limited understanding of the association of household air pollution and airway inflammation. We evaluated the cross-sectional association of FeNO with exposure to household air pollution (24-h average kitchen and personal fine particulate matter and black carbon; stove type) among 139 women in rural Honduras using traditional stoves or cleaner-burning Justa stoves. We additionally evaluated interaction by age. Results were generally consistent with a null association; we did not observe a consistent pattern for interaction by age. Evidence from ambient and household air pollution regarding FeNO is inconsistent, and may be attributable to differing study populations, exposures, and FeNO measurement procedures (e.g., the flow rate used to measure FeNO).

Keywords: fractional exhaled nitric oxide; household air pollution; particulate matter.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Adult
Air Pollution
Air Pollution, Indoor / adverse effects*
Air Pollution, Indoor / analysis
Biomass
Breath Tests
Cooking
Cross-Sectional Studies
Exhalation
Family Characteristics
Female
Honduras
Household Articles
Humans
Inflammation / etiology*
Inhalation Exposure / adverse effects*
Inhalation Exposure / analysis
Middle Aged
Nitric Oxide / analysis*
Particulate Matter / analysis
Rural Population
Smoke / adverse effects*
Smoke / analysis

Substances

Particulate Matter
Smoke
Nitric Oxide

Grants and funding

R21ES022810/ES/NIEHS NIH HHS/United States