Immunologic reconstitution following hematopoietic stem cell transplantation despite lymph node paucity in NF-κB-inducing kinase deficiency

J Allergy Clin Immunol. 2019 Mar;143(3):1240-1243.e4. doi: 10.1016/j.jaci.2018.11.003. Epub 2018 Nov 14.

Abstract

This case demonstrates successful immune reconstitution following hematopoietic stem cell transplantation in NIK deficiency.

Publication types

  • Case Reports
  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line
  • Child
  • Child, Preschool
  • Hematopoietic Stem Cell Transplantation*
  • Humans
  • Immunologic Deficiency Syndromes / genetics
  • Immunologic Deficiency Syndromes / immunology*
  • Infant
  • Lymph Nodes / immunology*
  • Male
  • NF-kappaB-Inducing Kinase
  • Protein Serine-Threonine Kinases / deficiency*
  • Protein Serine-Threonine Kinases / genetics

Substances

  • Protein Serine-Threonine Kinases