Abstract
Of 14 patients with obsessive-compulsive disorder who entered an 8-week open trial of buspirone, none improved. The ineffectiveness of buspirone may shed light on the serotonergic hypothesis that has been proposed for this disorder.
MeSH terms
-
Adult
-
Ambulatory Care
-
Buspirone / therapeutic use*
-
Clinical Trials as Topic
-
Female
-
Humans
-
Male
-
Obsessive-Compulsive Disorder / drug therapy*
-
Obsessive-Compulsive Disorder / physiopathology
-
Obsessive-Compulsive Disorder / psychology
-
Personality Inventory
-
Psychiatric Status Rating Scales
-
Serotonin / physiology